Rynier Mark Bernardo represented Eastern Province at various youth tournaments. In 2007, he played at the Under-16 Grant Khomo Week and in 2008 at the Under-18 Academy week, resulting in his inclusion in the SA Schools Academy team the same year. He also played at the 2009 Under-18 Craven Week tournament.
Between 2010 and 2012, Bernardo represented the EP u. 19 and u.21 sides in the Under-19 Provincial Championship and the Under-21 competition.
He made his first-class debut for Eastern Province in the 2012 Vodacom Cup competition, coming on as a third-minute substitute in their match against near neighbours Border Bulldogs. Rynier made one more substitute appearance in that competition. He then started the games against the Boland Cavaliers and the quarter-final against the Pumas.
His Currie Cup debut came a few months later against the SWD Eagles in the 2012 Currie Cup First Division competition. He made six appearances in total in that competition. Also, He started both promotion/relegation games against the Toyota Free State Cheetahs.
Bernardo was named in the Southern Kings squad for the 2013 Super Rugby season. An injury to Steven Sykes saw him included for their match against the Crusaders in Christchurch. He substituted Adongo to make his Super Rugby debut. Another substitute appearance followed in their next match against the Hurricanes before he made his first start in the competition in the dramatic 28–28 draw against the Brumbies in Canberra. Bernardo started their next match against the Rebels in Melbourne.
With the Kings not playing Super Rugby in 2014, Bernardo joined the Cheetahs for pre-season training before the 2014 Super Rugby season. However, he was not named in their final squad and returned to Port Elizabeth.
Bernardo joined Welsh Pro12 side Ospreys from 2014 until 2017. In 2015-'16, he suffered a dislocated kneecap which ruled him out for the rest of the season.
In June 2016, Bernardo joined another Welsh Pro12 side, Scarlets.
After the 2017–'18 European season, Bernardo returned to South Africa to join the Toyota Cheetahs for the 2017 Currie Cup Premier Division season.
Bernardo joined Canon Eagles for the 2018–'19 Top League season. After seven games, he re-joined the Toyota Cheetahs in 2021 and played in all four Preparation-Series matches.
He was a regular member of the Cheetah team. A shoulder injury in a Currie Cup match on 15th January 2022 against Griquas in Bloemfontein put him on the sideline for most of the season. In a Currie Cup match against the Pumas in Bloemfontein on the 3rd June 2022, Bernardo was back at his post next to his regular lock partner Victor Sekekete.
By the end of the Cheetahs' Currie Cup season on 18th June 2022, Bernardo had already played 48 matches for the Toyota Cheetahs.